I was going to start a thread on this myself. When I started on medication about four years ago I ballooned 15kg in about three months. I was on zyprexa, dothep, xanax, and sleeping pills. Everyone I met that was taking zyprexa gained a lot of weight. As well as increasing appetite, some medications make the body retain water. A side effect of many of these drugs is fatigue, so exercising is more difficult. When I came off zyprexa about two and a half years ago, I lost about 5kg in a few weeks, eventually all the weight came off, but it was short-lived and I've since gained over half the weight back. Even when I was back to my original weight people continually asked me if I was pregnant or how far along I was
So for me, medication made me very bloated and lethargic. I'm happy to say that I am only on a small amount of Zoloft at the moment, and am looking forward to being drug-free and healthy in the near future!